A Wearable Textile 3D Gesture Recognition Sensor Based on Screen-Printing Technology

[EN] Research has developed various solutions in order for computers to recognize hand gestures in the context of human machine interface (HMI). The design of a successful hand gesture recognition system must address functionality and usability. The gesture recognition market has evolved from touchpads to touchless sensors, which do not need direct contact. Their application in textiles ranges from the field of medical environments to smart home applications and the automotive industry. In this paper, a textile capacitive touchless sensor has been developed by using screen-printing technology. Two different designs were developed to obtain the best configuration, obtaining good results in both cases. Finally, as a real application, a complete solution of the sensor with wireless communications is presented to be used as an interface for a mobile phone.The work presented is funded by the Conselleria d'Economia Sostenible, Sectors Productius i Treball, through IVACE (Instituto Valenciano de Competitividad Empresarial) and cofounded by ERDF funding from the EU. Application No.: IMAMCI/2019/1. This work was also supported by the Spanish Government/FEDER funds (RTI2018-100910-B-C43) (MINECO/FEDER).Ferri Pascual, J.; Llinares Llopis, R.; Moreno Canton, J.; Ibáñez Civera, FJ.; Garcia-Breijo, E. (2019). A Wearable Textile 3D Gesture Recognition Sensor Based on Screen-Printing Technology. Sensors. 19(23):1-32. https://doi.org/10.3390/s19235068S1321923Chakraborty, B. K., Sarma, D., Bhuyan, M. K., & MacDorman, K. F. (2017). Review of constraints on vision‐based gesture recognition for human–computer interaction. IET Computer Vision, 12(1), 3-15. doi:10.1049/iet-cvi.2017.0052Zhang, Z. (2012). Microsoft Kinect Sensor and Its Effect. IEEE Multimedia, 19(2), 4-10. doi:10.1109/mmul.2012.24Rautaray, S. S. (2012). Real Time Hand Gesture Recognition System for Dynamic Applications. International Journal of UbiComp, 3(1), 21-31. doi:10.5121/iju.2012.3103Karim, R. A., Zakaria, N. F., Zulkifley, M. A., Mustafa, M. M., Sagap, I., & Md Latar, N. H. (2013). Telepointer technology in telemedicine : a review. BioMedical Engineering OnLine, 12(1), 21. doi:10.1186/1475-925x-12-21Santos, L., Carbonaro, N., Tognetti, A., González, J., de la Fuente, E., Fraile, J., & Pérez-Turiel, J. (2018). Dynamic Gesture Recognition Using a Smart Glove in Hand-Assisted Laparoscopic Surgery. Technologies, 6(1), 8. doi:10.3390/technologies6010008Singh, A., Buonassisi, J., & Jain, S. (2014). Autonomous Multiple Gesture Recognition System for Disabled People. International Journal of Image, Graphics and Signal Processing, 6(2), 39-45. doi:10.5815/ijigsp.2014.02.05Ohn-Bar, E., & Trivedi, M. M. (2014). Hand Gesture Recognition in Real Time for Automotive Interfaces: A Multimodal Vision-Based Approach and Evaluations. IEEE Transactions on Intelligent Transportation Systems, 15(6), 2368-2377. doi:10.1109/tits.2014.2337331Khan, S. A., & Engelbrecht, A. P. (2010). A fuzzy particle swarm optimization algorithm for computer communication network topology design. Applied Intelligence, 36(1), 161-177. doi:10.1007/s10489-010-0251-2Abraham, L., Urru, A., Normani, N., Wilk, M., Walsh, M., & O’Flynn, B. (2018). Hand Tracking and Gesture Recognition Using Lensless Smart Sensors. Sensors, 18(9), 2834. doi:10.3390/s18092834Zeng, Q., Kuang, Z., Wu, S., & Yang, J. (2019). A Method of Ultrasonic Finger Gesture Recognition Based on the Micro-Doppler Effect. Applied Sciences, 9(11), 2314. doi:10.3390/app9112314Lien, J., Gillian, N., Karagozler, M. E., Amihood, P., Schwesig, C., Olson, E., … Poupyrev, I. (2016). Soli. ACM Transactions on Graphics, 35(4), 1-19. doi:10.1145/2897824.2925953Sang, Y., Shi, L., & Liu, Y. (2018). Micro Hand Gesture Recognition System Using Ultrasonic Active Sensing. IEEE Access, 6, 49339-49347. doi:10.1109/access.2018.2868268Ferri, J., Lidón-Roger, J., Moreno, J., Martinez, G., & Garcia-Breijo, E. (2017). A Wearable Textile 2D Touchpad Sensor Based on Screen-Printing Technology. Materials, 10(12), 1450. doi:10.3390/ma10121450Nunes, J., Castro, N., Gonçalves, S., Pereira, N., Correia, V., & Lanceros-Mendez, S. (2017). Marked Object Recognition Multitouch Screen Printed Touchpad for Interactive Applications. Sensors, 17(12), 2786. doi:10.3390/s17122786Ferri, J., Perez Fuster, C., Llinares Llopis, R., Moreno, J., & Garcia‑Breijo, E. (2018). Integration of a 2D Touch Sensor with an Electroluminescent Display by Using a Screen-Printing Technology on Textile Substrate. Sensors, 18(10), 3313. doi:10.3390/s18103313Cronin, S., & Doherty, G. (2018). Touchless computer interfaces in hospitals: A review. Health Informatics Journal, 25(4), 1325-1342. doi:10.1177/1460458217748342Haslinger, L., Wasserthal, S., & Zagar, B. G. (2017). P3.1 - A capacitive measurement system for gesture regocnition. Proceedings Sensor 2017. doi:10.5162/sensor2017/p3.1Cherenack, K., & van Pieterson, L. (2012). Smart textiles: Challenges and opportunities. Journal of Applied Physics, 112(9), 091301. doi:10.1063/1.474272

The first time on the other side: PhD candidates experience in digital electronics practical sessions and final project

[EN] The university Lecturer Training Fellowship granted by the Spanish Ministry of Education implies the participation of the PhD candidates in the practical lessons of subjects related to their specialty. For the first time, two students were assigned to the high performance group in Digital Electronics in the Industrial Electronics and Automation degree, taught in the School of Design Engineering (ETSID) of the Universitat Politècnica de València (UPV). Taking advantage of the PhD candidates¿ easiness for comprehending the student¿s point of view, they were allowed to suggest and implement methodological modifications with the aim of improving the knowledge and skill transfer in the subject field. The main result was the development of a methodology which relates the practical and theoretical parts so they are interleaved, making it easier to comprehend, assimilate the concepts, and participate actively in the practical part gaining experience in the field. The subject is divided in three main parts: VHDL, microcontrollers and a final project. One of the PhD students was assigned to the VHDL part, the other one to the microcontroller part, and the final project was collaborative, with both participating in the organization and evaluation. This final project evaluates the innovation, creativity and entrepreneurship transversal skills of the students by entrusting them to develop a microcontroller code and to write the documentation about it, while participating in a car-like robot competition. This year, the competition was presented as a list of requirements the robots must meet before the deadline to access the ¿final test¿, in a way that was first implemented by the successful aerospace company SpaceX for the international Hyperloop Pod Competition series. This makes the deadlines and evaluation items very clear for both students and evaluators while leaving the door open to different ways of implementation using the knowledge acquired through the semester. This paper presents the thought process behind the methodology used during the subject and final project and the results obtained, alongside with the experience reported by both students and PhD intraining candidates.Terrés-Haro, JM.; Monreal-Trigo, J.; Ibáñez Civera, FJ.; Gil Sánchez, L.; Garcia-Breijo, E.; Laguarda-Miro, N. (2020). The first time on the other side: PhD candidates experience in digital electronics practical sessions and final project. IATED. 3845-3850. https://doi.org/10.21125/inted.2020.1284S3845385

Redesigning seminars in the subject sustainable development and environmental ethics for the new on-line higher education scenario due to COVID-19

[EN] Covid-19 has changed the global agenda this year 2020 and particularly since March when the disease disseminated and affected the whole world. Then, confinement strategies started in most of the countries affecting important humankind aspects such as economy, society, and many others. In an educational point of view, higher education has been suddenly forced to change from a traditional presential education structure to a non-presential learning-teaching framework based on virtual/on-line educational strategies. Particular efforts have been done at the Universitat Politècnica de València (UPV) and in its Design Engineering School (ETSID) to adapt their educational model to this unexpected situation. This paper shows the work conducted to redesign seminars in the subject Sustainable Development and Environmental Ethics according to the requirements of this new scenario. A preliminary SWOT analysis allowed to focus our redesigning efforts in specific aspects of the seminar: assuming the nonpresential scenario and adapting to this new reality, an appropriate and more effective information sharing, some visual aspects associated to the specific teamworking dynamics in the classroom, structure and seminar schedule were some of the aspects to be on in the redesigning process. Students¿ opinions and point of view were particularly considered in redesigning as they are intensively experiencing on-line education since confinement started. Finally, structure, tasks, schedule, attendance, results compilation and sharing, and assessment were completely reconsidered and adapted. After this season¿s experience, development, results and students¿ feedback have been studied in depth. As a conclusion, the new redesigned seminar rises as a successful improved version of the activity being more dynamic, participative, and educationally functional. Although, there are important aspects that have been lost because they are linked to presential attendance and real teamworking in the classroom. Further efforts will be focused in diminishing these disadvantages.Laguarda-Miro, N.; Ibáñez Civera, FJ.; Gil Sánchez, L.; Garcia-Breijo, E.; Monreal-Trigo, J.; Terrés-Haro, JM. (2021). Redesigning seminars in the subject sustainable development and environmental ethics for the new on-line higher education scenario due to COVID-19. IATED. 5455-5460. https://doi.org/10.21125/inted.2021.1107S5455546

ON-LINE PRACTICES IN DIGITAL ELECTRONICS: THE REMOTELAB EXPERIENCE

[EN] Higher Education is given on-line since COVID-19 appeared and disseminated all over the world. Both students and teachers had little time to adapt to new learning-teaching applications and tools such as TEAMS or ZOOM. Subsequently, learning methodologies were also redesigned to be effective in a ¿non-presential¿ scenario that is mainly aseptic and depersonalized. When the state of emergency and confinement were over, the University had to reinvent educational methodologies. Then, new educational terms and expressions appeared in Higher Education and particularly in Engineering careers. Terms such as ¿partial attendance¿, ¿synchronous and asynchronous sessions¿ are nowadays present in our course guidelines but also in an unstable scenario in which higher education strategies are changing by the day. In this scenario, theory lessons have been easy to adapt to on-line education. In the same way, tutorials have become more fluid and flexible with this new system. On the other hand, difficulties to achieve an objective evaluation and conducting useful practice sessions are some of the identified weaknesses of the system. This paper focuses on these aspects studying the development of practices by local or on-line simulators and even by remote laboratories. A specific practice prototype is introduced, allowing ¿partial attendance¿ of the students, a part of them in-situ in the laboratory and another part attending the practice on-line by remote access to the practice board. This proposal lets us develop real practices with no need of synchronous assistance from the teachers by using a remote system and monitoring its development by webcamIbáñez Civera, FJ.; Laguarda-Miro, N.; Gil Sánchez, L.; Terrés-Haro, JM.; Monreal-Trigo, J.; Olguín Pinatti, CA. (2021). ON-LINE PRACTICES IN DIGITAL ELECTRONICS: THE REMOTELAB EXPERIENCE. IATED Academy. 5406-5411. https://doi.org/10.21125/inted.2021.1100S5406541

The interview as a learning tool: an experience of emotional motivation in engineering degrees

[EN] Technical studies in Higher Education have traditionally been seen as complex, difficult and abstract by students, and particularly when compared to university careers in the field of humanities, more related to social and human aspects. In the line of innovating in the field of engineering teaching, and with the intention of bringing engineering and learning strategies based on the social, this paper presents an experience of motivation and emotional bonding of students with their degrees in the field of industrial and aeronautical engineering. In this experience, the interview has been used as an educational tool. So, it has been applied to a very specific topic (sustainability and development in the industrial age) of the subject Sustainable Development and Environmental Ethics, included in the program of all the degrees at the School of Design Engineering of the Universitat Politècnica del València. The experience consisted in interviewing a family member or close person who had lived the industrialization age in the Spanish countryside, in order to enrichen the contents given at class with the personal experience of the interviewed relative. As a result, the experience is considered very satisfactory by the students as it allows them to reinforce the knowledge acquired in in the classroom being able to link theory to the personal experiences by people close to them who had the chance to experience the emergence of industrialization in the Spanish countryside. Thus, the interview provides students an emotional bond with the matter they are studying, achieving at least three main objectives, as the experience: 1) lets the students know about real experiences by relatives or close people in the industrialization age in Spain, 2) facilitates the contextualization of the matter in this specific historical period and 3) motivates the students to the subject and their careers.Laguarda-Miro, N.; Terrés-Haro, JM.; Monreal-Trigo, J.; Ibáñez Civera, FJ.; Gil Sánchez, L.; Olguín Pinatti, CA. (2020). The interview as a learning tool: an experience of emotional motivation in engineering degrees. IATED. 3938-3942. https://doi.org/10.21125/inted.2020.1092S3938394

Linking academic and labor training in finalist graduacte subjects: a strategy to improve students transversal competences

[EN] In the current presentation we propose the integration of training for employment in the last subjects of university degrees. Specifically, for this case, contents and activities of the elective subject ¿Organic Electronic and Processes in Electronic Design¿ are reformulated. This subject is included in the Degree in Industrial Electronics and Automation at the Universitat Politècnica de València (UPV). The aim of this proposal is to include training for employment (or external practices) and how to deal with the initial contacts with the destination work centre.Ibáñez Civera, FJ.; Laguarda-Miro, N.; Gil Sánchez, L.; Garcia-Breijo, E.; Olguín Pinatti, CA.; Monreal-Trigo, J.; Terrés-Haro, JM. (2019). Linking academic and labor training in finalist graduacte subjects: a strategy to improve students transversal competences. IATED. 3809-3812. https://doi.org/10.21125/inted.2019.0966S3809381

Colorimetric detection of hazardous gases using a remotely operated capturing and processing system

[EN] This paper presents an electronic system for the automatic detection of hazardous gases. The proposed system implements colorimetric sensing algorithms, thus providing a low-cost solution to the problem of gas sensing. It is remotely operated and it performs the tasks of image capturing and processing, hence obtaining colour measurements in RGB (Red Green Blue) space that are subsequently sent to a remote operator via the internet. A prototype of the system has been built to test its performance. Specifically, experiments have been carried out aimed at the detection of CO, CO2, NO, NO2, SO2 and formaldehyde at diverse concentrations by using a chromogenic array composed by 13 active and 2 inert compounds. Statistical analyses of the results reveal a good performance of the electronic system and the feasibility of remote hazardous gas detection using colorimetric sensor arrays.This research has been carried out in the framework of Project grant nos. MAT2012-38429-C04-01 and MAT2012-38429-C04-04, financed by the Spanish Ministry for Economy and Competitiveness. The authors also acknowledge the support of the Generalitat Valenciana through Project grant no. PROMETEOII/2014/047.Montes Robles, R.; Moragues Pons, ME.; Vivancos Bono, JL.; Ibáñez Civera, FJ.; Fraile Muñoz, R.; Martínez Mañez, R.; García Breijo, E. (2015). Colorimetric detection of hazardous gases using a remotely operated capturing and processing system. ISA Transactions. 59:434-442. https://doi.org/10.1016/j.isatra.2015.09.0104344425

Design of a low-cost equipment for optical hyperthermia

[EN] A laser equipment is presented which has been specifically designed for optical hyperthermia. Such specificity in the design has allowed implementation at costs significantly lower than other options currently available in the market. The developed equipment includes a 808 nm laser whose output power is up to 500 mW. It also incorporates additional devices that help the user in calibrating the system and supervising it while functioning. The performance of a prototype is tested by running two hyperthermia experiments: one involving gold nanorods, and the other using gold nanostars. The specific set-up of this prototype has allowed laser irradiation with radiated power densities up to 4W/cm(2). (C) 2016 Elsevier B.V. All rights reserved.This work has been carried out in the context of project "Development of electronic devices and equipment for detection and actuation based on new electronic technologies. Applications in the field of biomedicine" (grant number: MAT2015-64139-C4-3-R) and in coordination with project number MAT2015-64139-C4-1-R, both of them financed by the Spanish Ministry for Economy and Competitiveness in the framework of the Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016. Financial support from the Generalitat Valenciana (PROMETEOII/2014/047) and from the UPV (Erasmus Mundus EuroInkaNet project, 2013 call) are gratefully acknowledged too.Montes-Robles, R.; Hernández-Montoto, A.; Ibáñez Civera, FJ.; Masot Peris, R.; De La Torre-Paredes, C.; Martínez-Máñez, R.; Garcia-Breijo, E.... (2017). Design of a low-cost equipment for optical hyperthermia. Sensors and Actuators A Physical. 255:61-70. https://doi.org/10.1016/j.sna.2016.12.018S617025

Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser Induced Drug Release

[EN] Herein, a novel drug photorelease system based on gold nanostars (AuNSts), coated with a mesoporous silica shell and capped with paraffin as thermosensitive molecular gate, is reported. Direct measurements of the surface temperature of a single gold nanostar irradiated using a tightly focused laser beam are performed via a heat sensitive biological matrix. The surface temperature of a AuNSt increases by hundreds of degrees (degrees C) even at low laser powers. AuNSts coated with a mesoporous silica shell using a surfactant-templated synthesis are used as chemotherapeutic nanocarriers. Synthetic parameters are optimized to d avoid AuNSt reshaping, and thus to obtain nanoparticles with suitable and stable plasmonic properties for near-infrared (NIR) laser-triggered cargo delivery. The mesoporous silica-coated nanostars are loaded with doxorubicin (Dox) and coated with octadecyltrimethoxysilane and the paraffin heneicosane. The paraffin molecules formed a hydrophobic layer that blocks the pores, impeding the release of the cargo. This hybrid nanosystem exhibits a well-defined photodelivery profile using NIR radiation, even at low power density, whereas the nonirradiated sample shows a negligible payload release. Dox-loaded nanoparticles displayed no cytotoxicity toward HeLa cells, until they are irradiated with 808 nm laser, provoking paraffin melting and drug release. Hence, these novel, functional, and biocompatible nanoparticles display adequate plasmonic properties for NIR-triggered drug photorelease applications.The authors gratefully acknowledge financial support from the Spanish Government (Projects AGL2015-70235-C2-2-R and MAT2015-64139-C4-1-R), the Generalitat Valenciana (Project PROMETEOII/2014/047), and European Union (Programme European Union Action 2 Erasmus Mundus Partnerships, Grant-2014-0870/001-001). A. Samadi and L. B. Oddershede acknowledge financial support from the Novo Nordisk Foundation (NNF14OC0011361) and from the Danish National Research Foundation (DNRF116). A. H. Montoto thanks Erasmus Mundus Programme for his PhD scholarship at EurolnkaNet project. The authors thank UPV electron microscopy and CIPF confocal and electron microscopy services for technical support.Hernández-Montoto, A.; Montes-Robles, R.; Samadi, A.; Gorbe, M.; Terrés-Haro, JM.; Cao Milán, R.; Aznar, E.... (2018). Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser Induced Drug Release. ACS Applied Materials & Interfaces. 10(33):27644-27656. https://doi.org/10.1021/acsami.8b08395S2764427656103

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery

"This is the peer reviewed version of the following article: Hernández Montoto, Andy, Antoni Llopis-Lorente, Mónica Gorbe, José M. Terrés, Roberto Cao Milán, Borja Díaz de Greñu, María Alfonso, et al. 2019. Janus Gold Nanostars Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery. Chemistry A European Journal 25 (36). Wiley: 8471 78. doi:10.1002/chem.201900750, which has been published in final form at https://doi.org/10.1002/chem.201900750. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."[EN] Janus gold nanostar-mesoporous silica nanoparticle (AuNSt-MSNP) nanodevices able to release an entrapped payload upon irradiation with near infrared (NIR) light were prepared and characterized. The AuNSt surface was functionalized with a thiolated photolabile molecule (5), whereas the mesoporous silica face was loaded with a model drug (doxorubicin) and capped with proton-responsive benzimidazole-beta-cyclodextrin supramolecular gatekeepers (N 1). Upon irradiation with NIR-light, the photolabile compound 5 photodissociated, resulting in the formation of succinic acid, which induced the opening of the gatekeeper and cargo delivery. In the overall mechanism, the gold surface acts as a photochemical transducer capable of transforming the NIR-light input into a chemical messenger (succinic acid) that opens the supramolecular nanovalve. The prepared hybrid nanoparticles were non-cytotoxic to HeLa cells, until they were irradiated with a NIR laser, which led to intracellular doxorubicin release and hyperthermia. This induced a remarkable reduction in HeLa cells viability.The authors gratefully acknowledge financial support from the Spanish Government [Projects MAT2015-64139-C4-1-R, AGL2015-70235-C2-2-R and SAF2017-84689-R (MINECO/AEI/FEDER, UE)], the Generalitat Valenciana (Project PROMETEO2018/024) and European Union (Erasmus Mundus Programme, Action 2, grant agreement number 2014-0870/001001). A.H. thanks the Erasmus Mundus Programme for his PhD scholarship through the EuroInkaNet project. A.L.-L. thanks "La Caixa" Banking Foundation for his PhD scholarship.Hernández-Montoto, A.; Llopis-Lorente, A.; Gorbe, M.; Terrés-Haro, JM.; Cao Milán, R.; Díaz De Greñu-Puertas, B.; Alfonso-Navarro, M.... (2019). Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery. Chemistry - A European Journal. 25(36):8471-8478. https://doi.org/10.1002/chem.201900750S847184782536Yang, P., Gai, S., & Lin, J. (2012). Functionalized mesoporous silica materials for controlled drug delivery. Chemical Society Reviews, 41(9), 3679. doi:10.1039/c2cs15308dSancenón, F., Pascual, L., Oroval, M., Aznar, E., & Martínez-Máñez, R. (2015). Gated Silica Mesoporous Materials in Sensing Applications. ChemistryOpen, 4(4), 418-437. doi:10.1002/open.201500053Giménez, C., Climent, E., Aznar, E., Martínez-Máñez, R., Sancenón, F., Marcos, M. D., … Rurack, K. (2014). Towards Chemical Communication between Gated Nanoparticles. Angewandte Chemie International Edition, n/a-n/a. doi:10.1002/anie.201405580Giménez, C., Climent, E., Aznar, E., Martínez-Máñez, R., Sancenón, F., Marcos, M. D., … Rurack, K. (2014). Über den chemischen Informationsaustausch zwischen gesteuerten Nanopartikeln. Angewandte Chemie, 126(46), 12838-12843. doi:10.1002/ange.201405580Llopis-Lorente, A., Díez, P., Sánchez, A., Marcos, M. D., Sancenón, F., Martínez-Ruiz, P., … Martínez-Máñez, R. (2017). 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Annual Review of Biomedical Engineering, 15(1), 253-282. doi:10.1146/annurev-bioeng-071812-152409Hernández Montoto, A., Montes, R., Samadi, A., Gorbe, M., Terrés, J. M., Cao-Milán, R., … Martínez-Máñez, R. (2018). Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release. ACS Applied Materials & Interfaces, 10(33), 27644-27656. doi:10.1021/acsami.8b08395De la Torre, C., Domínguez-Berrocal, L., Murguía, J. R., Marcos, M. D., Martínez-Máñez, R., Bravo, J., & Sancenón, F. (2018). ϵ -Polylysine-Capped Mesoporous Silica Nanoparticles as Carrier of the C 9h Peptide to Induce Apoptosis in Cancer Cells. Chemistry - A European Journal, 24(8), 1890-1897. doi:10.1002/chem.201704161Teruel, A. H., Pérez-Esteve, É., González-Álvarez, I., González-Álvarez, M., Costero, A. M., Ferri, D., … Sancenón, F. (2018). Smart gated magnetic silica mesoporous particles for targeted colon drug delivery: New approaches for inflammatory bowel diseases treatment. Journal of Controlled Release, 281, 58-69. doi:10.1016/j.jconrel.2018.05.007García-Fernández, A., García-Laínez, G., Ferrándiz, M. L., Aznar, E., Sancenón, F., Alcaraz, M. J., … Orzáez, M. (2017). Targeting inflammasome by the inhibition of caspase-1 activity using capped mesoporous silica nanoparticles. Journal of Controlled Release, 248, 60-70. doi:10.1016/j.jconrel.2017.01.002Rastogi, S. K., Anderson, H. E., Lamas, J., Barret, S., Cantu, T., Zauscher, S., … Betancourt, T. (2017). Enhanced Release of Molecules upon Ultraviolet (UV) Light Irradiation from Photoresponsive Hydrogels Prepared from Bifunctional Azobenzene and Four-Arm Poly(ethylene glycol). ACS Applied Materials & Interfaces, 10(36), 30071-30080. doi:10.1021/acsami.6b16183Martínez-Carmona, M., Lozano, D., Baeza, A., Colilla, M., & Vallet-Regí, M. (2017). 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